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This page provides a comprehensive alphabetical list of prescription drugs that many be used to treat HD symptoms and supplements that may have neuroprotective qualities as based on preliminary reports in animal models. This is a good starting point if you want to learn more about a particular treatment.
We list treatments alphabetically by brand name and generic name. Each entry includes (in parentheses) alternate names for the treatment, symptoms treated, and whether the treatment has been reported to be neuroprotective in animal models. Treatment names are linked to pages that provide more details on the treatment. Since most treatments have both a brand name and a generic name, most treatments are listed twice.
Abilify® (aripiprazole) irritability, psychosis
alprazolam (Xanax®) anxiety
amantadine (Symmetrel®) chorea, rigidity
amitriptyline (Elavil®) depression, insomnia
Anafranil® (clomipramine) depression, obsessive compulsive behavior
Aricept® (donazepil)
aripiprazole (Abilify®) irritability, psychosis
Ativan® (lorazepam) anxiety, insomnia
atomoxetine (Strattera®) apathy
bupropion (Wellbutrin®) depression
BuSpar® (buspirone) anxiety, depression, irritability
buspirone (BuSpar®) anxiety, depression, irritability
carbamazipine (Tegretol®) irritability
carbedopa-levodopa (Sinemet®) rigidity
Celexa® (citalopram) anxiety, depression
citalopram (Celexa®) anxiety, depression
clomipramine (Anafranil®) depression, obsessive compulsive behavior
clonazepam (Klonopin®) anxiety
clozapine (Clozaril®) irritability, psychosis
Clozaril® (clozapine) irritability, psychosis
coenzyme Q-10 may be neuroprotective
creatine may be neuroprotective
Cymbalta® (duloxetine) anxiety, depression, obsessive compulsive behavior
Depakene® (valproate) irritability
Depakote® (divalproex) irritability
Desyrel® (trazodone) anxiety, depression, insomnia
Dexedrine® (dextroamphetamine) apathy
dextroamphetamine (Dexedrine®) apathy
DHA may be neuroprotective
diazepam (Valium®) anxiety, insomnia
divalproex (Depakote®) irritability
donazepil (Aricept®)
doxepin (Sinequan®) depression
duloxetine (Cymbalta®) anxiety, depression, obsessive compulsive behavior
Effexor® (venlafaxine) anxiety, depression, obsessive compulsive behavior
Elavil® (amitriptyline) depression, insomnia
escitalopram (Lexapro®) anxiety, depression, obsessive compulsive behavior
Exelon® (rivastigmine)
fluoxitine (Prozac®) anxiety, depression, obsessive compulsive behavior
fluvoxamine (Luvox®) anxiety, depression, obsessive compulsive behavior
gabapentin (Neurontin®)
Geodon® (ziprasidone) irritability, psychosis
Haldol® (haloperidol) chorea, irritability, psychosis
haloperidol (Haldol®) chorea, irritability, psychosis
imipramine (Tofranil®) depression, insomnia
Klonopin® (clonazepam) anxiety
Lamictal® (lamotrigine) depression, irritability
lamotrigine (Lamictal®) depression, irritability
Lexapro® (escitalopram) anxiety, depression, obsessive compulsive behavior
lorazepam (Ativan®) anxiety, insomnia
Luvox® (fluvoxamine) anxiety, depression, obsessive compulsive behavior
memantine (Namenda®) chorea, cognition
Minocin® (minocycline) may be neuroprotective
minocycline (Minocin®) may be neuroprotective
Mirapex® (pramipexole) rigidity
mirtazapine (Remeron®) depression, obsessive compulsive behavior
modafinil (Provigil®) apathy
Namenda® (memantine) chorea, cognition
NeuroCoat® (trehalose) may be neuroprotective
Neurontin® (gabapentin)
Nitoman® (Xenazine®, tetrabenazine) chorea
nortryptiline (Pamalor®) depression, insomnia
olanzapine (Zyprexa®) irritability, psychosis
omega-3 may be neuroprotective
Pamalor® (nortryptiline) depression, insomnia
paroxetine (Paxil®) anxiety, depression, obsessive compulsive behavior; may be neuroprotective
Paxil® (paroxetine) anxiety, depression, obsessive compulsive behavior; may be neuroprotective
pramipexole (Mirapex®) rigidity
Provigil® (modafinil) apathy
Prozac® (fluoxitine) anxiety, depression, obsessive compulsive behavior
quetiapine (Seroquel®) irritability, psychosis
Remeron® (mirtazapine) depression, obsessive compulsive behavior
Risperdal® (risperidone) irritability, psychosis
risperidone (Risperdal®) irritability, psychosis
rivastigmine (Exelon®)
Seroquel® (quetiapine) irritability, psychosis
sertraline (Zoloft®) anxiety, depression, obsessive compulsive behavior; may be neuroprotective
Sinemet® (carbedopa-levodopa) rigidity
Sinequan® (doxepin) depression
Strattera® (atomoxetine) apathy
Symmetrel® (amantadine) chorea, rigidity
Tegretol® (carbamazipine) irritability
tetrabenazine (Nitoman®, Xenazine®) chorea
Tofranil® (imipramine) depression, insomnia
trazodone (Desyrel®) anxiety, depression, insomnia
trehalose (NeuroCoat®) may be neuroprotective
Valium® (diazepam) anxiety, insomnia
valproate (Depakene®) irritability
venlafaxine (Effexor®) anxiety, depression, obsessive compulsive behavior
Wellbutrin® (bupropion) depression
Xanax® (alprazolam) anxiety
Xenazine® (Nitoman®, tetrabenazine) chorea
ziprasidone (Geodon®) irritability, psychosis
Zoloft® (sertraline) anxiety, depression, obsessive compulsive behavior; may be neuroprotective
Zyprexa® (olanzapine) irritability, psychosis
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