This page provides a comprehensive alphabetical list of prescription drugs that many be used to treat HD symptoms. This is a good starting point if you want to learn more about a particular treatment.

We list treatments alphabetically by brand name and generic name. Each entry includes (in parentheses) alternate names for the treatment, symptoms treated, and whether the treatment has been reported to be neuroprotective in animal models. Treatment names are linked to pages that provide more details on the treatment. Since most treatments have both a brand name and a generic name, most treatments are listed twice.

Abilify® (aripiprazole) irritability, psychosis

alprazolam (Xanax®) anxiety

amantadine (Symmetrel®) chorea, rigidity

amitriptyline (Elavil®) depression, insomnia

Anafranil® (clomipramine) depression, obsessive compulsive behavior

Aricept® (donepezil) cognition

aripiprazole (Abilify®) irritability, psychosis

Ativan® (lorazepam) anxiety, insomnia

atomoxetine (Strattera®) apathy

bupropion (Wellbutrin®) depression

BuSpar® (buspirone) anxiety, depression, irritability

buspirone (BuSpar®) anxiety, depression, irritability

carbamazepine (Tegretol®) irritability

carbidopa-levodopa (Sinemet®) rigidity

Celexa® (citalopram) anxiety, depression

citalopram (Celexa®) anxiety, depression

clomipramine (Anafranil®) depression, obsessive compulsive behavior

clonazepam (Klonopin®) anxiety

clozapine (Clozaril®) irritability, psychosis

Clozaril® (clozapine) irritability, psychosis

coenzyme Q-10 may be neuroprotective

creatine may be neuroprotective

Cymbalta® (duloxetine) anxiety, depression, obsessive compulsive behavior

Depakene® (valproate) irritability

Depakote® (divalproex) irritability

Desyrel® (trazodone) anxiety, depression, insomnia

Dexedrine® (dextroamphetamine) apathy

dextroamphetamine (Dexedrine®) apathy

DHA may be neuroprotective

diazepam (Valium®) anxiety, insomnia

divalproex (Depakote®) irritability

donepezil (Aricept®) cognition

doxepin (Sinequan®) depression

duloxetine (Cymbalta®) anxiety, depression, obsessive compulsive behavior

Effexor® (venlafaxine) anxiety, depression, obsessive compulsive behavior

Elavil® (amitriptyline) depression, insomnia

escitalopram (Lexapro®) anxiety, depression, obsessive compulsive behavior

Exelon® (rivastigmine) cognition

fluoxetine (Prozac®) anxiety, depression, obsessive compulsive behavior

fluvoxamine (Luvox®) anxiety, depression, obsessive compulsive behavior

gabapentin (Neurontin®) irritability

Geodon® (ziprasidone) irritability, psychosis

Haldol® (haloperidol) chorea, irritability, psychosis

haloperidol (Haldol®) chorea, irritability, psychosis

imipramine (Tofranil®) depression, insomnia

Klonopin® (clonazepam) anxiety

Lamictal® (lamotrigine) depression, irritability

lamotrigine (Lamictal®) depression, irritability

Lexapro® (escitalopram) anxiety, depression, obsessive compulsive behavior

lorazepam (Ativan®) anxiety, insomnia

Luvox® (fluvoxamine) anxiety, depression, obsessive compulsive behavior

memantine (Namenda®) chorea, cognition

Minocin® (minocycline) may be neuroprotective

minocycline (Minocin®) may be neuroprotective

Mirapex® (pramipexole) rigidity

mirtazapine (Remeron®) depression, obsessive compulsive behavior

modafinil (Provigil®) apathy

Namenda® (memantine) chorea, cognition

NeuroCoat® (trehalose) may be neuroprotective

Neurontin® (gabapentin) irritability

Nitoman® (tetrabenazine,Xenazine®) chorea

nortryptiline (Pamalor®) depression, insomnia

olanzapine (Zyprexa®) irritability, psychosis

omega-3 may be neuroprotective

Pamalor® (nortryptiline) depression, insomnia

paroxetine (Paxil®) anxiety, depression, obsessive compulsive behavior; may be neuroprotective

Paxil® (paroxetine) anxiety, depression, obsessive compulsive behavior; may be neuroprotective

pramipexole (Mirapex®) rigidity

Provigil® (modafinil) apathy

Prozac® (fluoxetine) anxiety, depression, obsessive compulsive behavior

quetiapine (Seroquel®) irritability, psychosis

Remeron® (mirtazapine) depression, obsessive compulsive behavior

Risperdal® (risperidone) irritability, psychosis

risperidone (Risperdal®) irritability, psychosis

rivastigmine (Exelon®) cognition

Seroquel® (quetiapine) irritability, psychosis

sertraline (Zoloft®) anxiety, depression, obsessive compulsive behavior; may be neuroprotective

Sinemet® (carbidopa-levodopa) rigidity

Sinequan® (doxepin) depression

Strattera® (atomoxetine) apathy

Symmetrel® (amantadine) chorea, rigidity

Tegretol® (carbamazepine) irritability

tetrabenazine (Nitoman®,Xenazine®) chorea

Tofranil® (imipramine) depression, insomnia

trazodone (Desyrel®) anxiety, depression, insomnia

trehalose (NeuroCoat®) may be neuroprotective

Valium® (diazepam) anxiety, insomnia

valproate (Depakene®) irritability

venlafaxine (Effexor®) anxiety, depression, obsessive compulsive behavior

Wellbutrin® (bupropion) depression

Xanax® (alprazolam) anxiety

Xenazine® (Nitoman®,tetrabenazine) chorea

ziprasidone (Geodon®) irritability, psychosis

Zoloft® (sertraline) anxiety, depression, obsessive compulsive behavior; may be neuroprotective

Zyprexa® (olanzapine) irritability, psychosis