Drugs that have been tried for rigidity were developed for similar symptoms in Parkinson's. There is almost no information on whether these drugs are effective or not.

Pramipexole (Mirapex®) This is a dopamine drug that is most often used in Parkinson's disease. Dosage starts at 0.125 mg three times a day, and is increased slowly by 0.125 mg every 3-7 days. Side effects include sleepiness and dry mouth as well as hallucinations (in Parkinson's).

Carbidopa-levodopa (Sinemet®) This is a dopamine drug that is used in Parkinson's disease. Side effects include nausea, dizziness, headache and hallucinations (in Parkinson's). This drug can make chorea worse, but is used for the rigid forms of HD.

Amantadine (Symmetrel®) This drug is most often used in Parkinson's disease. Note that it is also used in Huntington's to treat chorea. This drug may have different effects at different stages of disease.