In this section we describe supplements that appear to show some benefit in mouse model studies. It should be noted that results depend on which laboratory does the testing. Though a trend toward benefit has been seen for lower dose Coenzyme Q10, the larger 2Care testing high dose showed no benefit, and a trend toward harm.

The supplements described can be obtained over the counter without a prescription. But it is vitally important to remember two points: you still need a doctor, and you need to choose safest supplement products.

Why get a doctor? You need a doctor to keep you safe, because supplements can have as many side effects as prescription drugs. They can interact with other prescription medicines or other supplements to give harmful side effects. And you will need regular blood tests, particularly if you choose a higher dosage of supplement. Again, I recommend that very high doses be used only in the clinical trial situation.

Why best products? You need best products to keep you safe. Unlike prescription drugs, supplements are not regulated by any government agency such as the FDA. Some supplement products contain toxic by-products, while others don't contain the dosage listed on the bottle. Make sure that your supplements have been tested and certified by either Consumer Lab or United States Pharmacopeia.

High doses not advised: High doses of any supplement, particularly those with antioxidants may cause harm. [Stranges S 2007]

References

Stranges S, Marshall JR, Natarajan R, Donahue RP, Trevisan M, Combs GF, Cappuccio FP, Ceriello A, Reid ME. Effects of long-term selenium supplementation on the incidence of type 2 diabetes: a randomized trial. Ann Intern Med. 2007 Aug 21;147(4):217-23. Epub 2007 Jul 9. PubMed abstract