Healthy Life Style, BDNF and Neuroplasticity

Posted May 6, 2012 by LaVonne Goodman, M.D.

Why is a healthy life style important in HD?  A big part of the answer includes BDNF, the "Mircle Gro" chemical for the brain, and a complicated process called neuroplasticity, both of which are enhanced by healthy life style factors. The "plasticity" part of neuroplasticity refers to capacity to change, similar to how plastic is malleable and can be made into many shapes.  Similarly, neuroplasticity describes the ability of nerve cells to change -- based on various forces -- by making new, or stronger connections to other nerve cells in the brain. This is the brain process that makes learning and memory possible.  And vitally important in brain diseases, neuroplasticity is a process that can preserve brain function while damage occurs -- at least for a while.

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Treatment Guidelines for Huntington's: Who needs them?

Posted Sept 12, 2011 by LaVonne Goodman M.D.

During my years as an internal medicine physician, I have used standard of care guidelines for my patients with conditions like diabetes and heart disease. Guidelines are developed by experts in each disease who translate clinical trial evidence and/or expert experience into recommended care patterns for use in medical offices or at the bedside. When followed, guidelines have been central to improving the quality of care provided by all physicians whether they are specialists or generalists.   

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