Pridopidine and the Hope for HD Neuroprotection

Posted June 25, 2015 by LaVonne Goodman, M.D.

In a new laboratory study from Italy, investigators have reported a very exciting result for Huntington's (HD).  Pridopidine, the drug presently in clinical trial for HD was shown -- not just to treat motor symptoms -- but also to provide neuroprotective benefit in a genetic mouse model of Huntington's.

Though the important pridopidine human study, the PRIDE-HD trial has another year to be completed, and more time needed to complete analysis, this mouse study suggests we might get more than symptom benefit from this new drug.  Exciting indeed that it might give neuroprotection too.
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Informal (Family) Caregivers for HD

Posted May 5, 2015 by LaVonne Goodman, M.D.

Care is described as informal when provided by unpaid family members or friends, and formal when caretakers are paid. Though a small subset of individuals with HD are cared for in the home through end of life, formal paid home healthcare services are frequently utilized. However the vast majority of individuals with HD, as the intensity of care needs increase will transition to long-term care facilities. In this situation, many family caretakers continue to advocate for and provide care.

What is known about informal care in HD?

 

 

 


 


 

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Treatment Guidelines for Huntington's: Who needs them?

Posted by LaVonne Goodman M.D.

During my years as an internal medicine physician, I have used standard of care guidelines for my patients with conditions like diabetes and heart disease. Guidelines are developed by experts in each disease who translate clinical trial evidence and/or expert experience into recommended care patterns for use in medical offices or at the bedside. When followed, guidelines have been central to improving the quality of care provided by all physicians whether they are specialists or generalists.   

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